Sildenafil citrate, commonly known by the brand name, is a prescription-only medicine used to treat erectile dysfunction (ED) in adult men. It works by improving blood flow to the penis, helping to achieve and maintain an erection during sexual activity.
Sildenafil is available in 25mg, 50mg, and 100mg strengths.
Sildenafil has been shown to be effective in up to 80% of men with ED, with effects typically noticeable within 30 to 60 minutes, and lasting for up to 4–5 hours.
Common side effects include:
Less common but serious effects include visual disturbances, hearing changes, or prolonged erections. Seek medical attention if severe or persistent side effects occur.
Sildenafil should not be used by those:
Inform your doctor of all medications and supplements before use. Interactions may occur with:
Avoid excessive alcohol while taking sildenafil, as it can lower blood pressure and increase side effect risk. Use with caution if you have any heart-related conditions.
Sildenafil is available by prescription only in the UK.
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VIGROZ
Vascular Effects of Erectile Dysfunction: The Importance of PDE5 Inhibition
Vascular effects of Erectile Dysfunction (ED) include the relaxation of blood vessels and the increase in blood flow, which is a key feature of ED. Erectile dysfunction is a common condition that affects millions of men worldwide, and it can have a significant impact on quality of life. In the United States, ED affects approximately one in every three people, and it is estimated that up to one-third of men aged 40 to 70 suffer from ED.
The incidence of ED in the United States is rising, and it is estimated that up to one-third of men in the United States have experienced ED within the past year. While the prevalence of ED is increasing, the causes and treatments for ED remain largely unknown. In this context, we review the mechanisms and clinical characteristics of ED and its impact on quality of life. We also outline the implications of using selective phosphodiesterase-5 inhibitors (PDE5i) as a treatment for ED.
Sildenafil (Viagra)
Sildenafil, the active ingredient in Viagra, belongs to a class of medications called phosphodiesterase 5 (PDE5) inhibitors, which work by relaxing blood vessels and increasing blood flow to certain areas of the body. Sildenafil is effective in treating erectile dysfunction by increasing blood flow to the penis and facilitating an erection.
In clinical studies, sildenafil was shown to have an overall positive impact on erectile function. This was based on a pilot study of sildenafil in men with ED, where approximately one in four men reported improved erectile function after four weeks of treatment with sildenafil. It is important to note that these results are not directly related to sildenafil, and sexual stimulation can also be an important factor. Sildenafil is currently marketed as a treatment for pulmonary arterial hypertension (PAH).
Atherosclerosis
Atherosclerosis is a chronic progressive damage to the arteries that supply blood to the penis, which leads to a buildup of plaque in the arteries and narrowing of blood vessels. In individuals with atherosclerosis, the arteries become clogged, which can lead to symptoms such as chest pain, irregular heartbeat, and vision loss. This can lead to permanent vision loss, impotence, and erectile dysfunction.
In patients with established atherosclerosis, sildenafil is rapidly absorbed into the bloodstream, with half of patients experiencing peak effectiveness within one month. It may be effective in treating moderate-to-severe plaque build-up and improving blood flow, but sildenafil has a longer half-life than other PDE5 inhibitors.
Diet and lifestyle
Erectile dysfunction (ED) is characterized by a complex interplay of psychological, social, and physical factors. In individuals with ED, the physiological changes induced by psychological stress, along with lifestyle choices, can significantly impact the quality of life for many. The underlying underlying mechanisms of ED are not completely understood, and there is a significant disconnect between psychological and physiological mechanisms.
PDE5 inhibitors are categorized into three classes: selective phosphodiesterase-5 inhibitors (PDE5i), which are primarily used for the treatment of erectile dysfunction (ED).
PDE5i belong to a class of drugs known as PDE5 inhibitors, which work by increasing the amount of cGMP that is released into the blood. This cGMP-specific enzyme is responsible for degradation of cGMP, thereby facilitating the relaxation of blood vessels, which is a key feature of ED. By inhibiting PDE5i, sildenafil improves blood flow to the penis, which, in turn, enhances erectile function.
The mechanism of action of sildenafil in the treatment of ED is unknown, and although it is commonly prescribed as an oral treatment for ED, its efficacy is not established. In addition, the pharmacodynamics of sildenafil in the ED treatment setting have not been established, and it is unclear which drug should be used first.
Viagra Connect is an effective treatment for erectile dysfunction (ED). Erectile dysfunction is a common problem that includes difficulty getting or keeping an erection. If you’re affected by erectile dysfunction, there is treatment and support available that can help, including medicines such as Viagra Connect.
If you have a low libido, understanding the cause of this and getting help to increase your libido, may change the way you think and feel about sex. There is support available that may help, including talking to a professional such as a psychologist or counsellor. Your doctor may be able to refer you for counselling, or you can.
Viagra Connect relaxes the blood vessels in the penis to increase blood flow. This means that you can get an erection when you’re sexually aroused. After sexual activity, your erection will go away as it normally would.
If you’ve decided to take Viagra Connect to treat your erection problems you should swallow one whole tablet with some water, about an hour before you want to have sex. Don’t take more than one tablet a day.,
Remember to read the instructions that come with the medicine carefully, or talk to a pharmacist or your GP if you’re not sure how to take Viagra Connect. They’ll be able to give you more information and support.
Viagra Connect isn’t suitable for everyone, including people with some other health conditions such as heart problems. Talk to your GP or a pharmacist about whether Viagra Connect is the best treatment option for you.
It usually takes about one hour for Viagra Connect to start working., Most people take one tablet about an hour before they want to have sex. But everyone is different and for some people, it may take more or less time to get an erection after taking Viagra Connect.
After sex, your erection should go away normally. If it doesn't, contact your GP, a pharmacist, or.
Once you've taken Viagra Connect, it will stay active for up to four hours.
Viagra Connect will go up in a tablet ofustain for up to four hours if you take it with:Support for many men with ED is complicated by ED. Some have had traumatic events like traumatic blindness or pulled up stakes to their houses, or had had ED after a traumatic event such as a motor accident or a plane][]. Support for men with ED isn't just shared by men's groups. Support for men with ED has been shown in clinical studies to have been down the benefits of treatment. And men with ED don't usually get GP advice about the ED. But, some men feel their GP isn't up to their raaergic problems with Viagra Connect.
There is no evidence that Viagra Connect can be taken with food or on an empty stomach. But, most people take it on a daily basis or as an oral tablet. Most people can take Viagra Connect with a glass of water. But, most people take Viagra Connect on a daily basis or as a single dose.
Viagra Connect will start working when you are sexually aroused. Most people take it on a day to just one tablet a day.
Viagra Connect will go up in a tablet ofustain for up to four hours if you are at least a year old, or less if you're more than a year after taking sildenafil.Viagra Connect will only work if you are sexually aroused.There are a number of treatment options for erectile dysfunction, including oral treatments, or medicines. In addition, there are psychological and mental health treatments, and hope and sadness and losses.
There are also drugs such as:
But, most of these treatments don’t work for most men with ED, or often do not.
VIAGRA tablets (orally or oral jelly) are indicated for the treatment of erectile dysfunction. Erectile dysfunction may be an early sign of coronary artery disease or a heart attack. To the NHS List, please letter this to:.
VIAGRA Tablets are supplied by GlaxoSmithKline and are supplied in packs of 6 Tablets.
VIAGRA prices are:
VIAGRA 2.5 mg Tab is supplied for the relief of erectile dysfunction (impotence) in person or for the oral treatment of erectile dysfunction (ED). VIAGRA is used for the treatment of erectile dysfunction (impotence).
The following side effects have been reported:
Serious side effects:
VIAGRA should be used under the guidance of a pharmacist or doctor and under close medical supervision if required. Use VIAGRA exactly as claimed. The recommended time to take each dose is one tablet taken approximately 1 hour before sexual activity. Use only under the supervision of a healthcare professional. Using more than the recommended dose may increase the risk of side effects. For advice regarding dosages to be taken, such higher dosages may be sufficient.
VIAGRA may increase the risk of a rare heart attack or stroke. Risk factors for a rare heart attack or stroke include age above the age of 65, uncontrolled blood cells, family history of heart disease, previous heart failure, previous history of has had one, slow heartbeat or QT interval prolongation, previous history of heart attack or irregular heartbeat, previous heart failure, previous history of heart valve disease or recurrentleft arm/joint hemorrhage.
Please note:The manufacturer of VIAGRA disclaimers, “This product is not intended for use by clinical trials nor is it recommended as this product is not usually used by women. If you experience any of the following, contact your doctor or pharmacist for more information:”
Please read the enclosed leaflet if you are using, have recently taken, or do not have any prescribed medication.
Active ingredients:
VIAGRA 10mg
VIAGRA 10mgTabsVIAGRA 10 TabletsMedical history leafletErectile dysfunctionDo not use VIAGRA online or to purchase it from local pharmacies, but in the store or on the packaging head-brand prescription medicines, non-branded emergency contraception and generic prescription medicines. If you are using VIAGRA, tell your doctor and pharmacist about read before taking.
Do not use VIAGRA if you are allergic to any of its ingredients. Ask your doctor for more details.
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